Do cupcakes take less time to bake than a cake? Yes, but not by as much as you might think. The bake time for cupcakes is between 15 and 25 minutes at 350 degrees, while a full cake will take between 25 and 35 minutes. Whether you decide to make cupcakes, a layer cake, or a sheet cake, you’ll be able to test them for doneness in the same way: Just stick a toothpick into the center of the cake (or into the center of a cupcake that’s toward the middle of your cupcake pan) and pull it back out. If the toothpick comes out clean, your cake is ready to come out of the oven.