Our recommended temperature for baked salmon fillet is 375 degrees. At that temperature, your salmon will take around 20 minutes to cook, depending on the thickness of your fillet. We suggest making baked salmon wrapped in foil, which helps it to steam in its own juices so it won’t dry out. If you’re in a hurry, you can crank up the oven temperature; obviously, the higher the oven temperature, the shorter the bake time. It will only take 15 minutes to bake salmon at 400 degrees or 10 minutes at 425 degrees, but be careful: There’s a fine line between underdone and overdone, and it’s easier to cross that line in a hotter oven.