The bake time for spaghetti squash may vary depending on how tender you like your “spaghetti,” but in general, you’ll want to bake your squash for no more than 40 minutes in a 400-degree oven. Before you put the squash in the oven, cut it in half and scoop out the seeds and stringy parts in the middle. Place the halves cut side down on a pan, prick holes in the skin, and bake. You can tell if your spaghetti squash is ready if spaghetti-like strands easily release from the skin of the squash. If they do not, continue baking it and check back every 5 minutes until it’s done.